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M.I.N.I.

MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW

English Version 5.0.0

DSM-IV

USA: D. Sheehan, J. Janavs, R. Baker, K. Harnett-Sheehan, E. Knapp, M. Sheehan

University of South Florida - Tampa

FRANCE: Y. Lecrubier, E. Weiller, T. Hergueta, P. Amorim, L. I. Bonora, J. P. Lépine

Hôpital de la Salpétrière - Paris

© Copyright 1992-2006 Sheehan DV & Lecrubier Y

All rights reserved. No part of this document may be reproduced or transmitted in any form, or

by any means, electronic or mechanical, including photocopying, or by any information storage or

retrieval system, without permission in writing from Dr. Sheehan or Dr. Lecrubier. Researchers

and clinicians working in nonprofit or publicly owned settings (including universities, nonprofit

hospitals, and government institutions) may make copies of a M.I.N.I. instrument for their own

clinical and research use. DISCLAIMER

Our aim is to assist in the assessment and tracking of patients with greater efficiency and accuracy. Before action is taken on

any data collected and processed by this program, it should be reviewed and interpreted by a licensed clinician.

This program is not designed or intended to be used in the place of a full medical and psychiatric evaluation by a qualified

licensed physician – psychiatrist. It is intended only as a tool to facilitate accurate data collection and processing of

symptoms elicited by trained personnel.

M.I.N.I. 5.0.0 (July 1, 2006)

Patient Name: Patient Number:

Time Interview Began:

Date of Birth: Time Interview Ended:

Interviewer’s Name:

Date of Interview: Total Time:

MEETS

MODULES TIME FRAME CRITERIA DSM-IV ICD-10

†

A MAJOR DEPRESSIVE EPISODE Current (2 weeks) 296.20-296.26 Single F32.x

†

Recurrent 296.30-296.36 Recurrent F33.x

†

MDE WITH MELANCHOLIC FEATURES Current (2 weeks) 296.20-296.26 Single F32.x

Optional 296.30-296.36 Recurrent F33.x

†

B DYSTHYMIA Current ( Past 2 years) 300.4 F34.1

†

C SUICIDALITY Current (

Past Month)

† † †

Risk: Low Medium High

†

D MANIC EPISODE Current 296.00-296.06 F30.x-F31.9

†

Past †

HYPOMANIC EPISODE Current 296.80-296.89 F31.8-F31.9/F34.0

†

Past †

E PANIC DISORDER Current (Past Month

) 300.01/300.21 F40.01-F41.0

†

Lifetime †

F AGORAPHOBIA Current 300.22 F40.00

†

G SOCIAL PHOBIA (Social Anxiety Disorder) Current (

Past Month) 300.23 F40.1

†

H OBSESSIVE-COMPULSIVE DISORDER Current (

Past Month) 300.3 F42.8

†

I POSTTRAUMATIC STRESS DISORDER Current (

Past Month) 309.81 F43.1

†

J ALCOHOL DEPENDENCE Past 12 Months 303.9 F10.2x

†

ALCOHOL ABUSE Past 12 Months 305.00 F10.1

†

Past 12 Months

K SUBSTANCE DEPENDENCE (Non-alcohol) 304.00-.90/305.20-.90 F11.1-F19.1

†

SUBSTANCE ABUSE (Non-alcohol) Past 12 Months 304.00-.90/305.20-.90 F11.1-F19.1

†

L PSYCHOTIC DISORDERS Lifetime 295.10-295.90/297.1/ F20.xx-F29

†

Current 297.3/293.81/293.82/

293.89/298.8/298.9

†

Lifetime

MOOD DISORDER WITH PSYCHOTIC FEATURES 296.24/296.34/296.44 F32.3/F33.3/

†

Current 296.24/296.34/296.44 F30.2/F31.2/F31.5

F31.8/F31.9/F39

†

M ANOREXIA NERVOSA Current ( Past 3 Months) 307.1 F50.0

†

N BULIMIA NERVOSA Current ( Past 3 Months) 307.51 F50.2

†

Current 307.1 F50.0

ANOREXIA NERVOSA, BINGE EATING/PURGING TYPE

M.I.N.I. 5.0.0 (July 1, 2006) 2 †

O GENERALIZED ANXIETY DISORDER Current (

Past 6 Months) 300.02 F41.1

†

P ANTISOCIAL PERSONALITY DISORDER Lifetime 301.7 F60.2

Optional

Which problem troubles you the most? Indicate your response by checking the appropriate check box(es).

M.I.N.I. 5.0.0 (July 1, 2006) 3

GENERAL INSTRUCTIONS

The M.I.N.I. was designed as a brief structured interview for the major Axis I psychiatric disorders in DSM-IV and ICD-10.

Validation and reliability studies have been done comparing the M.I.N.I. to the SCID-P for DSM-III-R and the CIDI (a structured

interview developed by the World Health Organization for lay interviewers for ICD-10). The results of these studies show that the

M.I.N.I. has acceptably high validation and reliability scores, but can be administered in a much shorter period of time (mean 18.7 ±

11.6 minutes, median 15 minutes) than the above referenced instruments. It can be used by clinicians, after a brief training session.

Lay interviewers require more extensive training.

INTERVIEW:

In order to keep the interview as brief as possible, inform the patient that you will conduct a clinical interview that is more

structured than usual, with very precise questions about psychological problems which require a yes or no answer.

GENERAL FORMAT:

The M.I.N.I. is divided into modules identified by letters, each corresponding to a diagnostic category.

•At the beginning of each diagnostic module (except for psychotic disorders module), screening question(s) corresponding to

the main criteria of the disorder are presented in a gray box.

•At the end of each module, diagnostic box(es) permit the clinician to indicate whether diagnostic criteria are met.

CONVENTIONS:

Sentences written in « normal font » should be read exactly as written to the patient in order to standardize the assessment of

diagnostic criteria. » should not be read to the patient. They are instructions for the interviewer to assist in the

Sentences written in « CAPITALS

scoring of the diagnostic algorithms.

Sentences written in « bold » indicate the time frame being investigated. The interviewer should read them as often as

necessary. Only symptoms occurring during the time frame indicated should be considered in scoring the responses.

Answers with an arrow above them ( ) indicate that one of the criteria necessary for the diagnosis(es) is not met. In this

case, the interviewer should go to the end of the module, circle « NO » in all the diagnostic boxes and move to the next

module.

When terms are separated by a slash (/) the interviewer should read only those symptoms known to be present in the patient

(for example, question H6).

Phrases in (parentheses) are clinical examples of the symptom. These may be read to the patient to clarify the question.

RATING INSTRUCTIONS:

All questions must be rated. The rating is done at the right of each question by circling either Yes or No. Clinical judgment

by the rater should be used in coding the responses. The rater should ask for examples when necessary, to ensure accurate

coding. The patient should be encouraged to ask for clarification on any question that is not absolutely clear.

of the question is taken into account by the patient (for example, time

The clinician should be sure that each dimension

frame, frequency, severity, and/or alternatives).

Symptoms better accounted for by an organic cause or by the use of alcohol or drugs should not be coded positive in the

M.I.N.I. The M.I.N.I. Plus has questions that investigate these issues.

For any questions, suggestions, need for a training session, or information about updates of the M.I.N.I., please contact :

David V Sheehan, M.D., M.B.A. Yves Lecrubier, M.D. / Thierry Hergueta, M.S.

University of South Florida College of Medicine INSERM U302

3515 East Fletcher Avenue Hôpital de la Salpétrière

Tampa, FL USA 33613-4788 47, boulevard de l’Hôpital

tel : +1 813 974 4544; fax : +1 813 974 4575 F. 75651 PARIS, FRANCE

e-mail : dsheehan@hsc.usf.edu tel : +33 (0) 1 42 16 16 59; fax : +33 (0) 1 45 85 28 00

e-mail : hergueta@ext.jussieu.fr

M.I.N.I. 5.0.0 (July 1, 2006) 4

A. MAJOR DEPRESSIVE EPISODE

( : , NO , )

MEANS GO TO THE DIAGNOSTIC BOXES CIRCLE IN ALL DIAGNOSTIC BOXES AND MOVE TO THE NEXT MODULE

A1 Have you been consistently depressed or down, most of the day, nearly NO YES

every day, for the past two weeks?

A2 In the past two weeks, have you been much less interested in most things or NO YES

much less able to enjoy the things you used to enjoy most of the time?

A1 A2 ? NO YES

IS OR CODED YES

A3 Over the past two weeks, when you felt depressed or uninterested: *

a Was your appetite decreased or increased nearly every day? Did your weight NO YES

(i.e., by ±5% of body weight

decrease or increase without trying intentionally

or ±8 lbs. or ±3.5 kgs., for a 160 lb./70 kg. person in a month)?

.

,

IF YES TO EITHER CODE YES

b Did you have trouble sleeping nearly every night (difficulty falling asleep, waking up NO YES

in the middle of the night, early morning wakening or sleeping excessively)? *

c Did you talk or move more slowly than normal or were you fidgety, restless NO YES

or having trouble sitting still almost every day?

d Did you feel tired or without energy almost every day? NO YES

e Did you feel worthless or guilty almost every day? NO YES

f Did you have difficulty concentrating or making decisions almost every day? NO YES

g Did you repeatedly consider hurting yourself, feel suicidal, or wish that you were dead? NO YES *

NO YES

5 (A1-A3) ?

ARE OR MORE ANSWERS CODED YES MAJOR DEPRESSIVE

EPISODE, CURRENT

4,

IF PATIENT HAS CURRENT MAJOR DEPRESSIVE EPISODE CONTINUE TO A

:

OTHERWISE MOVE TO MODULE B

A4 a During your lifetime, did you have other episodes of two weeks or more when you felt NO YES

depressed or uninterested in most things, and had most of the problems we just talked about?

NO YES

b In between 2 episodes of depression, did you ever have an interval

of at least 2 months, without any depression and any loss of interest? MAJOR DEPRESSIVE

EPISODE, RECURRENT

* If patient has Major Depressive Episode, Current, use this information in coding the corresponding questions on page 5 (A6d,

A6e).

M.I.N.I. 5.0.0 (July 1, 2006) 5

MAJOR DEPRESSIVE EPISODE WITH MELANCHOLIC FEATURES (optional)

( : , NO, )

MEANS GO TO THE DIAGNOSTIC BOX CIRCLE AND MOVE TO THE NEXT MODULE

IF THE PATIENT CODES POSITIVE FOR A CURRENT MAJOR DEPRESSIVE EPISODE (A3 = YES), EXPLORE THE FOLLOWING:

A5 a During the most severe period of the current depressive episode, did you lose almost NO YES

completely your ability to enjoy nearly everything?

b During the most severe period of the current depressive episode, NO YES

did you lose your ability to respond to things that previously gave

you pleasure, or cheered you up?

: When something good happens does it fail to make you feel better, even temporarily?

IF NO A5a A5b ? NO YES

IS EITHER OR CODED YES

A6 Over the past two week period, when you felt depressed and uninterested:

a Did you feel depressed in a way that is different from the kind of feeling NO YES

you experience when someone close to you dies?

b Did you feel regularly worse in the morning, almost every day? NO YES

c Did you wake up at least 2 hours before the usual time of awakening and NO YES

have difficulty getting back to sleep, almost every day?

d A3c (PSYCHOMOTOR )? NO YES

IS CODED YES RETARDATION OR AGITATION

e A3a ? NO YES

IS CODED YES FOR ANOREXIA OR WEIGHT LOSS

f Did you feel excessive guilt or guilt out of proportion to the reality of the situation? NO YES

NO YES

3 A6 ?

ARE OR MORE ANSWERS CODED YES Major Depressive Episode

with

Melancholic Features

Current

M.I.N.I. 5.0.0 (July 1, 2006) 6

B. DYSTHYMIA

( : , NO, )

MEANS GO TO THE DIAGNOSTIC BOX CIRCLE AND MOVE TO THE NEXT MODULE

' , .

IF PATIENT S SYMPTOMS CURRENTLY MEET CRITERIA FOR MAJOR DEPRESSIVE EPISODE DO NOT EXPLORE THIS MODULE

B1 Have you felt sad, low or depressed most of the time for the last two years? NO YES

B2 Was this period interrupted by your feeling OK for two months or more? NO YES

B3 During this period of feeling depressed most of the time:

a Did your appetite change significantly? NO YES

b Did you have trouble sleeping or sleep excessively? NO YES

c Did you feel tired or without energy? NO YES

d Did you lose your self-confidence? NO YES

e Did you have trouble concentrating or making decisions? NO YES

f Did you feel hopeless? NO YES

2 B3 ? NO YES

ARE OR MORE ANSWERS CODED YES NO YES

B4 Did the symptoms of depression cause you significant distress or impair

your ability to function at work, socially, or in some other important way? DYSTHYMIA

CURRENT

M.I.N.I. 5.0.0 (July 1, 2006) 7

C. SUICIDALITY

In the past month did you: Points

C1 Suffer any accident? NO YES 0

IF NO TO C1, SKIP TO C2; IF YES, ASK C1a,:

C1a Plan or intend to hurt yourself in that accident either passively or act